About Us

Astrea Bioseparations Ltd (formerly Prometic Bioseparations Ltd) has long been established as an expert in affinity chromatography and bioseparations. We provide custom adsorbents to solve client purification issues where standard solutions are either not suitable and/or available. Our custom services (Discover, Develop, Deliver…) include ligand design, adsorbent development, large scale adsorbent manufacture (up to 1,000L batch sizes) to GMP standards and GMP Ready pre-packed columns.

A total of 18 of Astrea’s adsorbents have been incorporated into FDA approved manufacturing processes which produce 12 approved pharmaceutical and medical products.

We can offer both standard ‘off-the-shelf’ adsorbents and bespoke adsorbents, which can be designed to meet specific purification/ manufacture criteria. These can be provided as adsorbents or pre-packed in Evolve®D GMP Ready Columns. We also supply a range of ‘semi-disposable’ bioprocess columns – Evolve® Bioprocess Columns.

Off the shelf adsorbents

Astrea has an extensive range of off-the-shelf bioseparation products, all available in a variety of formats to suit your requirements. Applications covered include:


    • Albumin and Albumin fusion proteins
    • Antibody and Antibody fragments
    • Recombinant proteins
    • Glycoprotein separation
    • Insulin & Insulin analogues
    • Plasma Proteins
    • Viral Vectors

Impurity removal:

  • Endotoxins
  • Serine Proteases
  • Host Cell Proteins
  • Isoagglutinins
  • Prions


Custom Affinity Adsorbents

Astrea also offers services to develop custom affinity adsorbents.

These include:

  • 30 years’ experience and success
  • Fully validated bespoke chromatography adsorbent
  • All associated process conditions for your target biomolecule
  • Maximum yield and purity
  • Minimum number of process steps
  • Screening Tools

To find out more about our custom services (Discover, Develop, Deliver…) please follow this link.