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Technical User Guides
Technical User Guides
IsoClear B™ Technical User Guide
Version 3

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IsoClear B™
IsoClear B™

IsoClear B™

Affinity adsorbent for removal of anti- B Isoagglutinin antibodies from Plasma, Serum and IVIG solutions


For the reduction of isoagglutinin B in the manufacture of Intravenous immunoglobulin (IVIG) products.

Key Features:

  • Highly specific Type B trisaccharide blood group antigen ligand.
  • Ligands synthesised in-house to give security of supply.
  • Biocompatible polymethacrylate base matrix.
  • Operational conditions up to 500 cm/h (up to 1 bar).
  • Specific for anti-B isoagglutinins (IgM and IgG isotypes).
  • High performance (97% isoagglutinin clearance from plasma).
  • Robust, long life adsorbents capable of multiple cycles.

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