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10% Off First Online Order With Code "FirstOrder10"

PuraBead® Resins

Trusted by the global biopharmaceutical industry for over three decades

IEX

IEX

HIC

HIC

Affinity

Affinity

Mixed Mode Chromatography

Mixed Mode Chromatography

PuraBead® Base Matrix

PuraBead® Base Matrix

PuraBead® Resins form the foundation of Astrea Bioseparations’ chromatography portfolio, trusted by the global biopharmaceutical industry for over three decades. Built on our proprietary PuraBead® base matrix, our resins combine high mechanical strength, low backpressure, and robust scalability to deliver reliable purification across all stages of development and GMP manufacturing. The PuraBead® range spans multiple chromatographic modes, including Ion Exchange (IEX), Hydrophobic Interaction (HIC), Affinity, and Mixed-mode solutions. Each family is designed to provide distinct selectivity and performance advantages, offering purification tools to tackle everything from routine antibody processing to the most challenging viral vector and advanced therapy separations. Proven in industry for decades, PuraBead® underpins multiple FDA-approved therapeutics, reinforcing its reliability and regulatory acceptance. As a cornerstone of Astrea Bioseparations, PuraBead® continues to enable the development and manufacture of life-changing therapies, delivering sustainable, scalable, and industry-proven performance.

Responsible, resilient, and ISO certified: Sustainability & Manufacturing Excellence

With over 30 years of chromatography manufacturing expertise, Astrea Bioseparations has established itself as a world-class provider of resins and adsorbents. Our vertically integrated operations span ligand development, bead formation, and packing — all managed under our ISO 9001:2015 accredited Quality Management System. This ensures rigorous quality, full traceability, and the confidence needed for GMP-compliant bioprocessing.

At the heart of our platform is the proprietary PuraBead® base matrix, produced via a unique solvent-free atomisation process. Unlike traditional bead-making techniques, this sustainable approach eliminates harmful solvents, reduces waste, and minimises environmental impact while maintaining mechanical strength, low backpressure, and consistent performance across scales. Combined with sustainably sourced agarose, PuraBead® is pioneering greener solutions for the biopharmaceutical industry.

To meet increasing global demand, we operate dual-site manufacturing with semi-continuous bead production and modular expansion capabilities. This strengthens security of supply, enabling us to deliver flexible, scalable solutions worldwide and reduce the risks of disruption for our customers. With proven adoption in multiple FDA-approved therapeutics and more than a decade of trusted partnership manufacturing Thermo Fisher’s CaptureSelect® range , Astrea Bioseparations continues to drive innovation, sustainability, and reliability in resin manufacturing.

  • Sustainable production — Solvent-free atomisation process minimises waste and environmental impact.
  • ISO 9001:2015 certified — Accredited global quality management system ensuring consistency and compliance.
  • Dual-site manufacturing — Semi-continuous production for scalability and resilient global supply.
  • Proven in industry — Technology trusted in multiple FDA-approved drugs and leading partnerships worldwide.
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