MAbsorbent A2P HF LL
£509.00 – £4,967.00
Description
MAbsorbents® were developed to mimic the Phe-132, Tyr-133 dipeptide binding site in the hydrophobic core structure of Protein A. We have developed IgG binding ligand libraries using a triazine scaffold substituted with aromatic amines. The resultant synthetic bifunctional ligands exhibit high affinities for human immunoglobulin G. Hence, MAbsorbent® A2P and A2P LL provide excellent purification performance.
MAbsorbents® effectively bind a wide variety of human and mammalian polyclonal antibodies (including bovine, mouse, sheep, goat, horse and rabbit) as well as whole monoclonal antibodies, humanized antibody chimeras and antibody fragments.
MAbsorbent® A2P P6HF LL is recommended for purification of IVIG (Intravenous Immunoglobulin) from Plasma and MAbsorbent® A2P P6HF for human or humanized antibodies.
Please contact us for pricing for pack sizes of 1 litre or more.
Additional information
| Weight | N/A |
|---|---|
| Dimensions | cm |
| Ligand | Synthetic aromatic triazine derivative |
| Absorbent appearance | Pink |
| Base Matrix | Highly cross-linked 6% near monodisperse agarose (PuraBead 6HF) |
| Particle Size | 90 ± 10µm |
| Binding Capacity | > 35 mg human IgG/ ml 20 to 30 mg MAb/ml |
| Opertating Pressure | Up to 3 bar (45 psi) |
| Operational flow rate | Up to 500 cm/hr with column diameter < 3cm Up to 200 cm/hr with column diameter > 5cm |
| Operating pH | pH2 to pH 14 (intermittent) |
| Chemical Stability | Stable in all commonly used buffers and solutions |
| Sanitization | 0.5 to 1.0M NaOH, 25◦C |
| Storage | 2-30◦C, 20% Ethanol |