MAbsorbent A2P HF
£594.00 – £5,114.00
MAbsorbents® were developed to mimic the Phe-132, Tyr-133 dipeptide binding site in the hydrophobic core structure of Protein A. We have developed IgG binding ligand libraries using a triazine scaffold substituted with aromatic amines. The resultant synthetic bifunctional ligands exhibit high affinities for human immunoglobulin G. Hence, MAbsorbent® A2P and A2P LL provide excellent purification performance.
MAbsorbents® effectively bind a wide variety of human and mammalian polyclonal antibodies (including bovine, mouse, sheep, goat, horse and rabbit) as well as whole monoclonal antibodies, humanized antibody chimeras and antibody fragments.
MAbsorbent® A2P P6HF LL is recommended for purification of IVIG (Intravenous Immunoglobulin) from Plasma and MAbsorbent® A2P P6HF for human or humanized antibodies.
Please contact us for pricing for pack sizes of 1 litre or more.
Synthetic aromatic triazine derivative
Highly cross-linked 6% near monodisperse agarose (PuraBead 6HF)
90 ± 10µm
> 35 mg human IgG/ ml 20 to 30 mg MAb/ml
Up to 3 bar (45 psi)
|Operational flow rate||
Up to 500 cm/hr with column diameter < 3cm Up to 200 cm/hr with column diameter > 5cm
pH2 to pH 14 (intermittent)
Stable in all commonly used buffers and solutions
0.5 to 1.0M NaOH, 25◦C
2-30◦C, 20% Ethanol