MiMode™ PuraBead® 96-well plate

High-throughput mixed-mode chromatography screening

The MiMode PuraBead® 96-well plate kit is a ready-to-use method development tool designed for high-throughput screening of mixed-mode chromatography conditions. Each well is pre-packed with 20 µL of Astrea Bioseparations’ mixed-mode chromatography resin.

Flexible operation

MiMode PuraBead® plates are compatible with both manual workflows (using multi-channel pipettes) and automated robotic systems. Their format supports high-throughput process development (HTPD) by enabling simultaneous screening of a wide range of chromatographic conditions.

Available formats

Plates are available in single-resin or multi-resin formats, offering flexibility for both targeted optimization and broader condition scouting.

Accelerated development

By allowing parallel analysis of multiple variables, these plates help quickly identify optimal process conditions across a broad experimental space. Once target conditions are identified, scale-up and process optimization are easily performed using compatible pre-packed columns such as 1 mL & 5 mL HT pre-packed columns, Evolve®R 5 mL or 50 mL columns, or through bulk resin on ÄKTA™ systems.

Kit components

Each kit includes:

• One MiMode PuraBead® 96-well plate
• A wash plate
• A collection plate

These components provide everything needed to carry out parallel experiments efficiently.

Astrea Bioseparations is a world class provider of chromatography adsorbent and resin services. With over 30 years of chromatography manufacturing expertise, we deliver a unique and trusted service in close partnership with our clients.

For more information, please don’t hesitate to reach out at sales@astrea-bio.com or visit astreabioseparations.com.