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10% Off First Online Order With Code "FirstOrder10"

Ion Exchange Chromatography Resins

Ion exchange chromatography (IEX) is a cornerstone of biopharmaceutical purification, offering powerful selectivity based on charge interactions. It is widely applied for the capture, intermediate purification, and polishing of proteins, antibodies, vaccines, and viral vectors, making it a trusted technique across research and regulated GMP manufacturing.

Astrea Bioseparations provides a comprehensive portfolio of PuraBead® IEX resins, including strong exchangers such as Q PuraBead® Edge and SP PuraBead® Edge, designed to deliver enhanced resolution for challenging separations. Established formats such as Q, SP, DEAE, and CM resins are also available, providing flexibility across diverse purification strategies.

All of our IEX resins are built on the proprietary PuraBead® base bead, manufactured using our unique atomisation technology. This base provides exceptional mechanical strength, low backpressure, and reproducible performance, ensuring robust scalability from discovery to commercial production.

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CM PuraBead® HF
CM PuraBead® HF
Ion Exchange (IEX) chromatography adsorbent with weak cation CM ligand
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DEAE PuraBead® HF
DEAE PuraBead® HF
Ion Exchange (IEX) chromatography adsorbent with weak anion DEAE ligand
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Q PuraBead® HF
Q PuraBead® HF
Ion Exchange (IEX) chromatography adsorbent with strong anion Q ligand
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SP PuraBead® HF
SP PuraBead® HF
Ion Exchange (IEX) chromatography adsorbent with strong cation SP ligand
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Q PuraBead® Edge
Q PuraBead® Edge
High resolution anion exchange chromatography resin on the trusted  PuraBead® platform. 
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SP PuraBead® Edge
SP PuraBead® Edge

SP PuraBead® Edge is a next-generation strong CEX adsorbent, featuring a sulphopropyl (SP) group attached to our advanced 65 µm PuraBead® Edge base bead. Our PuraBead® Edge resin is engineered for high-resolution polishing applications, offering short residence times and low back pressure. This resin is designed to enhance separation resolution, ideal when required for the capture and polish of positively charged species.

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