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MiMode™ PuraBead® CX2
MiMode™ PuraBead® CX2
MiMode™ PuraBead® CX2
MiMode™ PuraBead® CX2 Alternative Image
MiMode™ PuraBead® CX2 Alternative Image
MiMode™ PuraBead® CX2 Alternative Image

MiMode™ PuraBead® CX2

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MiMode™ PuraBead® CX2 is part of the cation exchange mixed-mode family, harnessing cationic, hydrophobic, and hydrogen-bonding interactions for powerful purification of positively charged biomolecules, including monoclonal antibodies, enzymes, and proteins with isoelectric points above neutral. By combining multiple binding interaction contributions, these resins provide enhanced flexibility in binding and release, supporting both capture and polishing steps in bioprocess workflows.
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Product overview

MiMode™ PuraBead® CX2 is a mixed-mode cation-exchange resin that combines ionic, hydrophobic, and hydrogen-bonding interactions to deliver broad selectivity for biomolecule purification.

The resin’s near-monodisperse agarose support ensures excellent flow and scalability, while chemical robustness allows for straightforward cleaning and re-use. Its performance is target-dependent, making MiMode™ PuraBead® CX2 particularly valuable as part of a structured screening approach during process development.

 

Key features of MiMode™ PuraBead® CX2

  • Multi-modal binding through cation exchange, hydrophobic, and hydrogen-bonding interactions.
  • Flexible use in bind-and-elute or flow-through polishing.
  • Robust and scalable agarose matrix.
  • Compatible with standard NaOH cleaning protocols.

 

Simplified workflow integration and scalability

MiMode™ PuraBead® CX2 is available in a range of screening and process formats offered by Astrea Bioseparations. Its mixed-mode nature means outcomes are highly dependent on target molecule characteristics, making early screening essential for identifying optimal purification conditions.

 

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