Blog

Exploring BioProcess International 2023

Revolutionizing Bioprocessing with AstreAdept® Technology: A Breakthrough in purification Innovation

Unleashing the Potential of Nanofiber Composites: Advancements in Purification and Beyond

Enhancing Productivity and Efficiency in Biomanufacturing

HCPure™: A Solution to Host Cell Protein Contamination in AAV Workflows

Increasing Processing Efficiency, Purity and Recovery of Lentiviral Particles for Viral Vector Development

Strengthen your bioprocessing adsorbent supply chain with Astrea Bioseparations

AstreAdept®: Nanofiber based Cell and Gene Therapy Purification Technology

Part Two: Has lentiviral purification been left behind?

Part One: Has lentiviral purification been left behind?

Discovering, Developing and Delivering New Purification Strategies for Novel Therapy Development

Determination of Dynamic Binding Capacity for Chromatography Adsorbent

How to determine the dynamic binding capacity of a chromatography adsorbent.

Performance Testing of Packed Columns

Guidelines from Astrea Bioseparations for Performance Testing of Packed Columns

Re-use, Cleaning and sanitization of IsoClear™ Affinity Adsorbents

A scale-down reuse study was performed on an automated chromatography workstation using a 2 mL IsoClear B™ column challenged with 50 CV of plasma per cycle.

Quality First!

At Astrea Bioseparations we put product quality first and have committed to become the first chromatography adsorbent manufacturer to achieve full GMP compliance!

Scaling up Production

Astrea Bioseparations has been manufacturing chromatography adsorbents on the Isle of Man since 1989. In this article we will update you on the expansion of our adsorbent manufacturing capacity.

Capture and purification of Fab fragments from human polyclonal IgG papain digest using Fabsorbent™ F1P HF

In response to demand we have developed an affinity adsorbent for the capture and purification of antibody fragments.

The Evolve® Process Column in NIBRT

User friendly and ergonomic; performance is comparable to more expensive columns and the single use aspect compares well to lengthy cleaning cycles.

Endotoxin removal & β-D-Glucan Interference

EtoxiClear™ has been shown to provide >3.4 log clearance of endotoxin from Fab fragments from an E. coli cell lysate, as well as from proteins such as IgG and HSA.

EtoxiClear®: An novel affinity adsorbent for the efficient removal of endotoxin

A number of methods have been adopted for the removal of endotoxin based on adsorption, in particular ion-exchange chromatography.