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In response to demand we have developed an affinity adsorbent for the capture and purification of antibody fragments.

We offer an extensive range of off-the-shelf Bioseparation products for the recovery and purification of biologicals as well as purification services including bespoke custom designed chromatography.

EtoxiClear™ has been shown to provide >3.4 log clearance of endotoxin from Fab fragments from an E. coli cell lysate, as well as from proteins such as IgG and HSA.

A scale-down reuse study was performed on an automated chromatography workstation using a 2 mL IsoClear B™ column challenged with 50 CV of plasma per cycle.

A number of methods have been adopted for the removal of endotoxin based on adsorption, in particular ion-exchange chromatography.

In this application note we describe how human serum albumin is captured and purified from human source plasma using Mimetic Blue® SA HL P6XL.

AlbuPure® can be used to capture and purify recombinant albumin-fusion proteins from cell culture supernatants with high purity and recovery.

Endotoxin or lipopolysaccharides (LPS) are highly toxic components of the cell wall of Gram-negative bacteria and are often present in significant amounts in bacterial cell expression systems.

Review useful insights and data highlighting the importance of protein glycosylation in Biopharmaceuticals.

Interest has been growing in the use of pre-packed disposable chromatography columns and in the use of disposable process fluid contact pathways.