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10% Off First Online Order With Code "FirstOrder10"

Commercial scale columns

Our columns are meticulously designed to meet the diverse needs of the biopharmaceutical industry, offering cutting-edge solutions for protein purification and separation processes.

Engineered with precision, ensuring optimal performance, reproducibility, and scalability. Whether you are involved in monoclonal antibody purification, vaccine development, or protein analytics, we can provide the perfect chromatography column to elevate your processes.

With a team of experts equipped with extensive experience in chromatography, our exceptional column packing service delivers bespoke column packing solutions tailored to your specific requirements. From custom resin selection to packing optimization, our services guarantee the highest quality and efficiency in your chromatography processes.

Evolve®D

Evolve®D pre-packed chromatography columns provide a reliable, ready-to-use solution for bioprocessing and commercial biomanufacturing, reducing the time, resources and complexity associated with in-house column packing.

Available in diameters of 7, 10, 14, 20, 25, 30, 35, 45 and 60 cm, with bed heights of 5 - 20 cm for smaller formats and 5 - 40 cm for larger formats, Evolve®D columns offer flexibility across a wide range of purification applications and manufacturing scales.

Columns can be packed with Astrea Bioseparations' chromatography resins or compatible third-party media, with access to a packing library covering over 90 commercial resins. Each column is packed to agreed specifications in an ISO 7 cleanroom environment, quality-tested and independently released by QA.

Every column is supplied with a Certificate of Analysis (CoA) and Regulatory Support File (RSF), supporting traceability and regulated manufacturing requirements. The robust, three-layer column design maintains packed-bed integrity during transportation and operation, while enabling ≥99% resin recovery under defined conditions.

With a target lead time of 5–8 weeks, Evolve®D offers a convenient, scalable solution supported by specialist chromatography expertise.

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*Bed heights of 5 - 40 cm are available for column diameters of 25, 30, 35, 45 and 60 cm. Larger 80 cm and 100 cm formats are in development

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Evolve® Process columns

High performance, easy to use technology with excellent flow distribution to support downstream bioprocessing applications.

Available in nine diameters and with scalable performance across the range, Evolve® Process columns are suitable for a variety of bioprocessing applications across a number of industrial processes.

The non-metallic flow path provides broad chemical compatibility, while refresh kits allow all wetted parts to be easily and cost-effectively replaced using refresh kits, reducing cross-contamination risk and minimizing the need for cleaning validation.

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Accessories

An extensive range of accessories and replacement parts are available for the Evolve® Process columns including refresh kits, a hygienic and economical solution to replace the entire wetted flow path to support single-use applications.

Accessories include:

  • Refresh kits to replace the wetted parts
  • Replacement bed supports, O-rings and connectors
  • Adaptors to facilitate connection to chromatography systems

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