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pDNA polish, at low operational pressure, after AEX primary capture or linearization of pDNA.

Chromatography capsule containing a hydrophobic AstreAdept® nanofiber matrix designed for removal of impurities after AEX primary capture of pDNA or post pDNA linearization at process development scale.

 

Key Features
  • High dynamic binding capacity
  • 4 mg/mL adsorbent, (4.7 kb) pDNA sequence
  • Low operational back pressure due to open unobstructive flow path
  • Suitable for large plasmids (tested up to 34 kB)
  • Sanitizable with 0.5 M NaOH

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