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Fast, reliable column packing with industry-leading turnaround

Accelerate bioprocess timelines with campaign-ready chromatography columns, pre-packed with your chosen resin

When development timelines are tight, waiting months for pre-packed columns can slow progress. Astrea Bioseparations helps you avoid column packing bottlenecks with ready-to-use chromatography columns, packed with your chosen resin and shipped in as little as 21 daysWe provide process-ready pre-packed columns designed to accelerate downstream processing, reduce operational risk, and ensure consistent, reproducible column performance.

What our column packing services can provide for your workflow:

  • Shipped in as little as 21 days to protect project timelines
  • Packed in ISO 7 cleanroom environments with ISO-9001 certified processes
  • Built & packed to process-ready quality standards
  • Manufactured across US and EU facilities for security of supply
  • Supplied with Certificate of Analysis and regulatory support documentation
  • End-to-end control of column components, assembly, and packing

Get a quote

Seamless scale-up from process validation to full commercial GMP production
Scale seamlessly from 1 cm to 60 cm with customizable bed height and resin selection, while recovering resin value through re-packing into process development scale formats. Operations are supported by ISO 7 clean room, GMP-ready environments, enabling rapid turnaround with a 3 to 5 week lead time and flexible dual-site packing across the UK and USA.

Predictable column delivery when timelines matter

Many bioprocess teams rely on large, established suppliers for pre-packed columns. However, as development pipelines grow and manufacturing timelines tighten, extended supplier lead times can become a challenge.

Astrea Bioseparations provides a reliable alternative for teams working under tight timelines. Our dedicated column packing capability supports predictable delivery of campaign-ready columns, helping reduce delays associated with long supplier lead times.

For teams managing multiple development programs or GMP manufacturing campaigns, consistent column availability can be as critical as column performance.

Astrea Bioseparations typically ships within 3–5 weeks

Our team works closely with you to ensure columns arrive when you need them, ready for immediate use.

Why outsource column packing?

Column packing is technically demanding, resource-intensive, and can place additional pressure and operational risk on internal downstream processing teams.

Even experienced teams may encounter challenges such as:

  • Delays from repacking or unsuccessful packing runs
  • Variability in packing between operators
  • Cross-contamination risks during cleaning
  • Limited internal capacity during critical development or manufacturing campaigns

Outsourcing column packing allows teams to focus on core process development and manufacturing tasks, while reducing the burden associated with internal packing and validation.

Interested to learn more about the benefits of outsourcing column packing?

Find additional resources with our outsourcing column packing brochure and blog.

Why choose Astrea Bioseparations column packing services

Accelerated delivery

Receive ready-to-use columns in as little as 3–5 weeks to help keep your processes on track.

Dedicated expertise

Reduce risk and ensure consistent, reproducible performance with expert column packing and robust quality systems.

Flexible resin selection

Support for over 45 commercially available chromatography resins to maintain established purification workflows and simplify scale-up.

Expert support

Expert support with our Field Application Specialist (FAS) team help minimize interruptions, troubleshoot challenges, and keep your process running smoothly.

Frequently packed resin media

    All

    • Matrix 215
    • MiMode PuraBead® (Astrea Bioseparations)
    • Amsphere A3 (JSR)
    • Protein G Sepharose High Performance (Cytiva)
    • Protein G Sepharose™ 4 Fast Flow (Cytiva)
    • MabSelect SuRe LX (Cytiva)
    • Capto MMC (Cytiva)
    • MabSelect PrismA (Cytiva)
    • Capto Core 400 (Cytiva)
    • Capto Butyl ImpRes (Cytiva)
    • MabSelect SuRe (Cytiva)
    • Purolite Praesto SP65 (Ecolab)
    • Capto PlasmidSelect (Cytiva)
    • Capto Adhere (Cytiva)
    • Capto Pheynl (High Sub) (Cytiva)
    • Capto Q ImpRes (Cytiva)
    • Amino Sepharose 6 Fast Flow (Cytiva)
    • Capto Q (Cytiva)
    • Capto  AVB (Cytiva)
    • Capto  Core 700 (Cytiva)
    • Q Sepharose Fast Flow (Cytiva)
    • Blue Sepharose Fast Flow (Cytiva)
    • Purolite Praesto Q65 (Ecolab)
    • MabCapture C Affinity Matrix (Thermo)
    • POROS XS (Thermo)
    • POROS CaptureSelect AAV9 Affinity Resin (Thermo)
    • POROS XQ (Thermo)
    • TOYOPEARL HW 75F (Tosoh)
    • TOYOPEARL GigaCap Q-650M (Tosoh)
    • POROS 50 HS (Thermo)
    • POROS 50 HQ (Thermo)
    • TSKgel Phenyl-5PW (20) (Tosoh)
    • POROS 50 D (Thermo)
    • POROS CaptureSelect AAVX Affinity Resin (Thermo)
    • Macro-Prep® High Q (Bio-Rad)
    • Fractogel® EMD DEAE (M) (Merck)
    • Cellufine MAX GS (JNC)
    • CHT Ceramic Hydroxyapatite (Bio-Rad)

    Agarose-based

    • Matrix 215
    • MiMode PuraBead® (Astrea Bioseparations)
    • Amsphere A3 (JSR)
    • Protein G Sepharose High Performance (Cytiva)
    • Protein G Sepharose™ 4 Fast Flow (Cytiva)
    • MabSelect SuRe LX (Cytiva)
    • Capto MMC (Cytiva)
    • MabSelect PrismA (Cytiva)
    • Capto Core 400 (Cytiva)
    • Capto Butyl ImpRes (Cytiva)
    • MabSelect SuRe (Cytiva)
    • Purolite Praesto SP65 (Ecolab)
    • Capto PlasmidSelect (Cytiva)
    • Capto Adhere (Cytiva)
    • Capto Pheynl (High Sub) (Cytiva)
    • Capto Q ImpRes (Cytiva)
    • Amino Sepharose 6 Fast Flow (Cytiva)
    • Capto Q (Cytiva)
    • Capto  AVB (Cytiva)
    • Capto  Core 700 (Cytiva)
    • Q Sepharose Fast Flow (Cytiva)
    • Blue Sepharose Fast Flow (Cytiva)
    • Purolite Praesto Q65 (Ecolab)
    • MabCapture C Affinity Matrix (Thermo)

    Polymethacrylate base

    • POROS XS (Thermo)
    • POROS CaptureSelect AAV9 Affinity Resin (Thermo)
    • POROS XQ (Thermo)
    • TOYOPEARL HW 75F (Tosoh)
    • TOYOPEARL GigaCap Q-650M (Tosoh)
    • POROS 50 HS (Thermo)
    • POROS 50 HQ (Thermo)
    • TSKgel Phenyl-5PW (20) (Tosoh)
    • POROS 50 D (Thermo)
    • POROS CaptureSelect AAVX Affinity Resin (Thermo)
    • Macro-Prep® High Q (Bio-Rad)
    • Fractogel® EMD DEAE (M) (Merck)

    Cellulose-based

    • Cellufine MAX GS (JNC)

    Other

    • CHT Ceramic Hydroxyapatite (Bio-Rad)

    Our column packing solutions

    Evolve®D column packing

    Scale your purification with ready-to-use Evolve®D columns, designed for pilot, clinical, and manufacturing-scale applications. Pre-packed with your chosen chromatography resin or media from the Astrea Bioseparations range, Evolve®D columns provide a flexible and scalable platform to support protein purification and contaminant removal workflows.

    With column diameters ranging from 70 mm to 600 mm, the platform supports seamless scale-up from development through to GMP manufacturing. Each column is packed in an ISO 7 cleanroom environment, performance tested prior to release, and supplied with a Certificate of Analysis and Regulatory Support File, ensuring consistent, reproducible performance and readiness for immediate use.

    Learn more

    SNAP® column packing
    Quickly move from process development to purification with ready-to-use SNAP® columns packed with your chosen resin. The SNAP® column range can be packed with virtually any chromatography media, making it well suited for process development, viral clearance studies, and small-scale purification workflows. Each pre-packed column undergoes performance testing prior to release, ensuring it arrives ready for immediate use without additional qualification.

    Learn more

    Column portfolio

    Explore our full range of chromatography columns designed to support purification workflows across development and production.

    Get in touch with our team

    Complete the inquiry form below and an Astrea Bioseparations representative will reach out within 48 hours to discuss your column packing inquiry.  See our Privacy Notice for details on how we use personal data.
     
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